Sodium Intake and All-Cause Mortality Over 20 Years in the Trials of Hypertension Prevention

The relationship between lower sodium intake and total mortality remains controversial.This study examined the relationship between well-characterized measures of sodium intake estimated from urinary sodium excretion and long-term mortality.Two trials, phase I (1987 to 1990), over 18 months, and phase II (1990 to 1995), over 36 months, were undertaken in TOHP (Trials of Hypertension Prevention), which implemented sodium reduction interventions....