The Germ Cell Fate of Cynomolgus Monkeys Is Specified in the Nascent Amnion
Abstract
The germ cell lineage ensures reproduction and heredity. The mechanism for germ cell specification in primates, including humans, has remained unknown. In primates, upon implantation the pluripotent epiblast segregates the amnion, an extra-embryonic membrane eventually ensheathing an embryo, and thereafter initiates gastrulation to generate three germ layers. Here, we show that in cynomolgus monkeys, the SOX17/TFAP2C/BLIMP1-positive primordial...
Paper Details
Title
The Germ Cell Fate of Cynomolgus Monkeys Is Specified in the Nascent Amnion
Published Date
Oct 1, 2016
Journal
Volume
39
Issue
2
Pages
169 - 185
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