Original paper

ASK1 controls spindle orientation and positioning by phosphorylating EB1 and stabilizing astral microtubules

Volume: 2, Issue: 1
Published: Oct 4, 2016
Abstract
Orientation and positioning of the mitotic spindle are involved in dictating cell division axis and cleavage site, and play important roles in cell fate determination and tissue morphogenesis. However, how spindle movement is controlled to achieve a defined alignment within the dividing cell is not fully understood. Here, we describe an unexpected role for apoptosis signal-regulating kinase 1 (ASK1) in regulating spindle behavior. We find that...
Paper Details
Title
ASK1 controls spindle orientation and positioning by phosphorylating EB1 and stabilizing astral microtubules
Published Date
Oct 4, 2016
Volume
2
Issue
1
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