TREATMENT OF VITREOMACULAR TRACTION WITH INTRAVITREAL PERFLUOROPROPANE (C3F8) INJECTION.

Published on Apr 1, 2017in Retina-the Journal of Retinal and Vitreous Diseases4.256
路 DOI :10.1097/IAE.0000000000001237
Nathan Steinle7
Estimated H-index: 7
,
Dilsher S. Dhoot11
Estimated H-index: 11
+ 6 AuthorsRobert L. Avery29
Estimated H-index: 29
Source
Abstract
Purpose:To assess the posterior vitreous release rates following a single, office-based intravitreal injection of expansile gas in treating vitreomacular traction.Methods:Thirty eyes of 29 consecutive patients with symptomatic vitreomacular traction received a single, office-based intravitreal injec
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#1David J. Warrow (Georgetown University)H-Index: 1
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Purpose To determine treatment outcomes of intravitreal ocriplasmin in symptomatic vitreomacular adhesion. Design Retrospective interventional case series. Methods setting: Private practice. study population: Thirty-five eyes (35 subjects) with symptomatic vitreomacular adhesion. intervention/observation: Intravitreal ocriplasmin injection from February to November 2013. main outcome measure: Vitreomacular adhesion resolution rate. Secondary endpoints included postinjection visual acuity and rat...
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#1Hao Feng (Yale University)H-Index: 8
#2Ron A. Adelman (Yale University)H-Index: 32
Purpose To evaluate the incidence and prevalence of cataract formation, progression, and extraction in patients that underwent vitreoretinal procedures and to evaluate factors that can potentially predispose patients to postoperative cataracts.
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#1Rishi P. Singh (Cleveland Clinic)H-Index: 14
#2Ang Li (Cleveland Clinic)H-Index: 8
Last. Peter K. Kaiser (Cleveland Clinic)H-Index: 105
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Objective To evaluate the anatomical and visual outcomes of patients treated with ocriplasmin for the treatment of symptomatic vitreomacular adhesion (sVMA), including vitreomacular traction syndrome and macular holes. Design Retrospective, interventional, single centre, case series. Participants Patients with sVMA. Intervention Patients were treated with a single intravitreal injection of 0.125鈥卪g ocriplasmin (Jetrea, Thrombogenics Inc, USA, Alcon/Novartis EU) with the reconstitution technique ...
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#1Jay S. Duker (Tufts University)H-Index: 96
#2Peter K. Kaiser (Cleveland Clinic)H-Index: 105
Last. Peter Stalmans (Katholieke Universiteit Leuven)H-Index: 27
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Objective The International Vitreomacular Traction Study (IVTS) Group was convened to develop an optical coherence tomography (OCT)-based anatomic classification system for diseases of the vitreomacular interface (VMI). Design The IVTS applied their clinical experience, after reviewing the relevant literature, to support the development of a strictly anatomic OCT-based classification system. Participants A panel of vitreoretinal disease experts was the foundation of the International Classificat...
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#1Timothy L Jackson (LSE: London School of Economics and Political Science)H-Index: 34
#2Elena NicodH-Index: 15
Last. Panos KanavosH-Index: 43
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Purpose:To determine the safety and efficacy of pars plana vitrectomy for vitreomacular traction.Methods:Articles reporting visual acuity change before and after pars plana vitrectomy were selected using a systematic literature review with predefined eligibility criteria. Visual acuities were conver
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#1Peter Stalmans (Katholieke Universiteit Leuven)H-Index: 27
#2Jay S. Duker (Tufts University)H-Index: 96
Last. Julia A. Haller (LMU: Ludwig Maximilian University of Munich)H-Index: 1
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Purpose: To review the role of optical coherence tomography (OCT) in diagnosis and management of vitreomacular disease and the impact of OCT on potential uses of ocriplasmin, a new pharmacologic vitreolysis agent recently approved by the U.S. Food and Drug Administration for the treatment of symptomatic vitreomacular adhesion. Methods: Analysis of current literature regarding OCT in diagnosis and management of vitreomacular interface disease. Results: Posterior vitreous detachment is typically a...
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#1K B Freund (NYU: New York University)H-Index: 5
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Last. Vinnie P. Shah (NYU: New York University)H-Index: 5
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Correlation of transient vision loss with outer retinal disruption following intravitreal ocriplasmin
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O VER THE PAST 2 DECADES, THANKS IN PART TO the development of optical coherence tomography, clinicians have gained increasing understanding of the critical role played by the vitreous in macular and retinal vascular disease. Age-related posterior vitreous detachment (PVD), once thought to be an acute event with precipitous onset and rapid progression, is now known to progress slowly over many months or years before its culmination at the time of vitreopapillary separation. In most individuals, ...
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#1Ian A Rodrigues (University of Cambridge)H-Index: 1
#2Alexandros Athanasios Stangos (University of Cambridge)H-Index: 2
Last. Timothy L Jackson (University of Cambridge)H-Index: 34
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Purpose To study the efficacy of a single intravitreal injection of expansile gas in releasing vitreomacular traction. Design Retrospective, interventional case series. Methods Fifteen eyes of 14 consecutive patients with symptomatic and persistent vitreomacular traction (>3聽months' duration) on spectral-domain optical coherence tomography (SD OCT) received a single intravitreal injection of 0.3聽mL 100% perfluoropropane (C 3 F 8 ) as an alternative to pars plana vitrectomy (PPV). Primary outcome...
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BACKGROUND Vitreomacular adhesion can lead to pathologic traction and macular hole. The standard treatment for severe, symptomatic vitreomacular adhesion is vitrectomy. Ocriplasmin is a recombinant protease with activity against fibronectin and laminin, components of the vitreoretinal interface. METHODS We conducted two multicenter, randomized, double-blind, phase 3 clinical trials to compare a single intravitreal injection of ocriplasmin (125 渭g) with a placebo injec tion in patients with sympt...
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#1Josef Guber (University of Basel)H-Index: 6
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To evaluate the indications and outcomes of perfluoropropane (C3F8) gas injection for symptomatic vitreomacular traction (VMT). A retrospective analysis of eyes with VMT treated with 0.3聽mL of C3F8 gas was performed. Patients were not asked to posture after gas injection. In phakic patients, cataract surgery was performed simultaneously. Patients were examined after one week and one month postoperatively. Twenty-nine consecutive eyes of 26 patients with symptomatic VMT who underwent pneumatic vi...
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#1Mark E. Seamone (U of A: University of Alberta)H-Index: 1
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Purpose:To determine whether pneumatic vitreolysis with intravitreal air is effective for focal vitreomacular traction (VMT).Methods:We conducted a retrospective consecutive case series of 20 eyes ...
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Abstract Objective To evaluate pneumatic vitreolysis (PVL) in eyes with vitreomacular traction (VMT) with and without full-thickness macular hole (FTMH). Design Two multi-center (28 sites) studies: one randomized clinical trial comparing PVL with observation (sham injection) for VMT without FTMH (Protocol AG), and a single-arm study assessing PVL for closure of FTMH (Protocol AH). Participants Participants were adults with central VMT in which the vitreomacular adhesion was 3000 渭m or less. In A...
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#1Mathias Maier (TUM: Technische Universit盲t M眉nchen)H-Index: 16
#2Ricarda G. Schumann (LMU: Ludwig Maximilian University of Munich)H-Index: 20
Last. C. HaritoglouH-Index: 10
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Unter 鈥濨iomarker鈥 versteht man 鈥瀊iologische Marker鈥, die objektiv auf den Gesundheitszustand hinweisen konnen. Neben funktionellen und zeitlichen Faktoren haben insbesondere bildgebende Biomarker in den letzten Jahren an Bedeutung gewonnen. Bei durchgreifenden und lamellaren Defekten der Makula wurden zahlreiche bildgebende Parameter beschrieben. Diese Erkenntnisse fuhrten fur beide Krankheitsbilder zu neuen Einteilungen, die sich auf wichtige 鈥濨iomarker鈥 dieser Krankheitsbilder und charakterist...
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PURPOSE: To compare the effect of intravitreal injections of air with gas on vitreomacular traction (VMT) release and attempt to analyze predictive factors for success. METHODS: The medical records of patients with symptomatic VMT undergoing intravitreal injections (0.3 mL) of either octafluoropropane (C3F8) or air were retrospectively reviewed. The VMT release (primary end point) and the best-corrected visual acuity (secondary end point) were noted 1 month after injection. At baseline and 1 mon...
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#1Neesurg Sunil Mehta (New York Eye and Ear Infirmary)H-Index: 1
#2Lalita Gupta (Case Western Reserve University)
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Purpose:To report a case of release of vitreomacular traction (VMT) in a patient with a full thickness macular hole (FTMH) immediately following pneumatic vitreolysis (PV) combined with head bobbin...
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#1Christina J. Flaxel (OHSU: Oregon Health & Science University)H-Index: 30
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#1Matthew Frederick Anderson (U of C: University of Calgary)
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PURPOSE: The optic nerve drusen (DON) are precisely described in many papers. But fewer papers evaluate real haemodynamics parameters (HP) in DON. Clinically, it has been shown, that the development and progression of visual field changes in DON is closely related to the hemodynamics of the ocular vascular supply - the optic nerve. DON can visually overlap the excavation optic disc, making it difficult to evaluate scotomas of the visual field in glaucoma. METHODS: HP was prospectively evaluated ...
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#1H眉seyin Baran 脰zdemir (UHSA: University of Health Sciences Antigua)H-Index: 4
#2艦eng眉l 脰zdek (Gazi University)H-Index: 3
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Objectives: To evaluate the posterior vitreous release rates after a single injection of expansile gas in patients with vitreomacular traction (VMT) syndrome with or without associated full-thickness macular hole (FTMH). Materials and Methods: Thirteen eyes of 12 consecutive patients with VMT (11 eyes) or VMT+FTMH (2 eyes) were reviewed retrospectively. Intravitreal injection of 0.3 mL of pure sulfur hexafluoride (SF6) (9 eyes) or perfluoropropane (C3F8) (4 eyes) was performed. Bobbing the head ...
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