Cross‐linking in children with keratoconus: a systematic review and meta‐analysis

Keratoconus can behave more aggressively in pediatric than in adult patients. We systematically reviewed the literature to determine the effectiveness of corneal collagen cross‐linking (CXL) in children. For this study, MEDLINE ® and Cochrane databases were searched for all studies examining the effects of standard, trans‐epithelial or accelerated CXL protocols in patients age 18 years or younger. Primary outcomes were; uncorrected visual acuity...