Vascular smooth muscle cell durotaxis depends on extracellular matrix composition

Volume: 113, Issue: 40, Pages: 11190 - 11195
Published: Oct 4, 2016
Abstract
Mechanical compliance has been demonstrated to be a key determinant of cell behavior, directing processes such as spreading, migration, and differentiation. Durotaxis, directional migration from softer to more stiff regions of a substrate, has been observed for a variety of cell types. Recent stiffness mapping experiments have shown that local changes in tissue stiffness in disease are often accompanied by an altered ECM composition in vivo....
Paper Details
Title
Vascular smooth muscle cell durotaxis depends on extracellular matrix composition
Published Date
Oct 4, 2016
Volume
113
Issue
40
Pages
11190 - 11195
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