Romosozumab Treatment in Postmenopausal Women with Osteoporosis.

Volume: 375, Issue: 16, Pages: 1532 - 1543
Published: Sep 18, 2016
Abstract
BackgroundRomosozumab, a monoclonal antibody that binds sclerostin, increases bone formation and decreases bone resorption. MethodsWe enrolled 7180 postmenopausal women who had a T score of –2.5 to –3.5 at the total hip or femoral neck. Patients were randomly assigned to receive subcutaneous injections of romosozumab (at a dose of 210 mg) or placebo monthly for 12 months; thereafter, patients in each group received denosumab for 12 months, at a...
Paper Details
Title
Romosozumab Treatment in Postmenopausal Women with Osteoporosis.
Published Date
Sep 18, 2016
Volume
375
Issue
16
Pages
1532 - 1543
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