SIRT1 controls cell proliferation by regulating contact inhibition

Volume: 478, Issue: 2, Pages: 868 - 872
Published: Sep 1, 2016
Abstract
Contact inhibition keeps cell proliferation in check and serves as a built-in protection against cancer development by arresting cell division upon cell-cell contact. Yet the complete mechanism behind this anti-cancer process remains largely unclear. Here we present SIRT1 as a novel regulator of contact inhibition. SIRT1 performs a wide variety of functions in biological processes, but its involvement in contact inhibition has not been explored...
Paper Details
Title
SIRT1 controls cell proliferation by regulating contact inhibition
Published Date
Sep 1, 2016
Volume
478
Issue
2
Pages
868 - 872
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