Proximity Labeling Reveals Molecular Determinants of FGFR4 Endosomal Transport
Abstract
The fibroblast growth factor receptors (FGFRs) are important oncogenes promoting tumor progression in many types of cancer, such as breast, bladder, and lung cancer as well as multiple myeloma and rhabdomyosarcoma. However, little is known about how these receptors are internalized and down-regulated in cells. We have here applied proximity biotin labeling to identify proteins involved in FGFR4 signaling and trafficking. For this purpose we...
Paper Details
Title
Proximity Labeling Reveals Molecular Determinants of FGFR4 Endosomal Transport
Published Date
Sep 26, 2016
Journal
Volume
15
Issue
10
Pages
3841 - 3855
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