Metabolic determinants of the immune modulatory function of neural stem cells

Volume: 13, Issue: 1
Published: Sep 2, 2016
Abstract
Neural stem cells (NSCs) display tissue trophic and immune modulatory therapeutic activities after transplantation in central nervous system disorders. The intercellular interplay between stem cells and target immune cells is increased in NSCs exposed to inflammatory cues. Here, we hypothesize that inflammatory cytokine signalling leads to metabolic reprogramming of NSCs regulating some of their immune modulatory effects.NSC lines were prepared...
Paper Details
Title
Metabolic determinants of the immune modulatory function of neural stem cells
Published Date
Sep 2, 2016
Volume
13
Issue
1
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