MMP-14 and CD44 in Epithelial-to-Mesenchymal Transition (EMT) in ovarian cancer

MC Vos; Eva Hollemans; Nicole P. M. Ezendam; Harry Feijen; Dorry Boll; Brenda M. Pijlman; Hans van der Putten; Paul J. J. M. Klinkhamer; Toin H. van Kuppevelt; Anneke A. M. van der Wurff

doi:https://doi.org/10.1186/s13048-016-0262-7

doi.org/10.1186/s13048-016-0262-7

MMP-14 and CD44 in Epithelial-to-Mesenchymal Transition (EMT) in ovarian cancer

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..., Anneke A. M. van der Wurff

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Journal of Ovarian Research4.00

Volume: 9, Issue: 1

Published: Sep 2, 2016

Abstract

To investigate the expression of MMP-14 and CD44 as well as epithelial-to-mesenchymal transition(EMT)-like changes in ovarian cancer and to determine correlations with clinical outcome.In 97 patients with ovarian cancer, MMP-14 and CD44 expression as determined by immunohistochemistry was investigated in relation to EMT-like changes. To determine this, immunohistochemical staining of E-cadherin and vimentin was performed.Patients with expression...

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Paper Details

Title

MMP-14 and CD44 in Epithelial-to-Mesenchymal Transition (EMT) in ovarian cancer

DOI

doi.org/10.1186/s13048-016-0262-7

Published Date

Sep 2, 2016

Journal

Journal of Ovarian Research

Volume

9

Issue

1

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