Evaluation of intravoxel incoherent motion fitting methods in low‐perfused tissue

Purpose To investigate the robustness of constrained and simultaneous intravoxel incoherent motion (IVIM) fitting methods and the estimated IVIM parameters ( D, D* and f ) for applications in brain and low‐perfused tissues. Materials and Methods Model data simulations relevant to brain and low‐perfused tumor tissues were computed to assess the accuracy, relative bias, and reproducibility (CV%) of the fitting methods in estimating the IVIM...