Endoplasmic reticulum proteostasis in hepatic steatosis.
Abstract
Hepatic steatosis, the first step in the progression of nonalcoholic fatty liver disease, is characterized by triglyceride accumulation in hepatocytes and is highly prevalent in people with obesity. Although initially asymptomatic, hepatic steatosis is an important risk factor for the development of hepatic insulin resistance and type 2 diabetes mellitus and can also progress to more severe pathologies such as nonalcoholic steatohepatitis, liver...
Paper Details
Title
Endoplasmic reticulum proteostasis in hepatic steatosis.
Published Date
Aug 12, 2016
Journal
Volume
12
Issue
12
Pages
710 - 722
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Notes
History