Neurocognitive function varies by IDH1 genetic mutation status in patients with malignant glioma prior to surgical resection
Abstract
Patients with malignant gliomas present with variation in neurocognitive function (NCF) not attributable to lesion size or location alone. A potential contributor is the rate at which tumors grow, or “lesion momentum.” Isocitrate dehydrogenase 1 wild type (IDH1-WT) are more proliferative and aggressive than IDH1-mutant (IDH1-M) tumors. We hypothesized that patients with IDH1-WT would exhibit worse NCF than patients with IDH1-M tumors....
Paper Details
Title
Neurocognitive function varies by IDH1 genetic mutation status in patients with malignant glioma prior to surgical resection
Published Date
Aug 30, 2016
Journal
Volume
18
Issue
12
Pages
1656 - 1663
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