Dynamic DNA methylation regulates neuronal intrinsic membrane excitability
Abstract
Epigenetic modifications, such as DNA cytosine methylation, contribute to the mechanisms underlying learning and memory by coordinating adaptive gene expression and neuronal plasticity. Transcription-dependent plasticity regulated by DNA methylation includes synaptic plasticity and homeostatic synaptic scaling. Memory-related plasticity also includes alterations in intrinsic membrane excitability mediated by changes in the abundance or activity...
Paper Details
Title
Dynamic DNA methylation regulates neuronal intrinsic membrane excitability
Published Date
Aug 23, 2016
Journal
Volume
9
Issue
442
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Notes
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