Increased oxygen exposure alters collagen expression and tissue architecture during ligature‐induced periodontitis

Background and Objective The aim of this study was to evaluate the effects of increased oxygen availability on gene expression and on collagen deposition/maturation in the periodontium following disease. Material and Methods Male Wistar rats had ligatures placed around their molars to induce periodontal disease, and a subset of animals underwent hyperbaric oxygen ( HBO ) treatment for 2 h twice per day. At 15 and 28 d, tissue gene expression of...