Mathematical modeling of gonadotropin-releasing hormone signaling

Volume: 449, Pages: 42 - 55
Published: Jul 1, 2017
Abstract
Gonadotropin-releasing hormone (GnRH) acts via G-protein coupled receptors on pituitary gonadotropes to control reproduction. These are Gq-coupled receptors that mediate acute effects of GnRH on the exocytotic secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), as well as the chronic regulation of their synthesis. GnRH is secreted in short pulses and GnRH effects on its target cells are dependent upon the dynamics of...
Paper Details
Title
Mathematical modeling of gonadotropin-releasing hormone signaling
Published Date
Jul 1, 2017
Volume
449
Pages
42 - 55
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