Transplantation of tissue engineering neural network and formation of neuronal relay into the transected rat spinal cord

Volume: 109, Pages: 40 - 54
Published: Aug 5, 2016
Abstract
Severe spinal cord injury (SCI) causes loss of neural connectivity and permanent functional deficits. Re-establishment of new neuronal relay circuits after SCI is therefore of paramount importance. The present study tested our hypothesis if co-culture of neurotrophin-3 (NT-3) gene-modified Schwann cells (SCs, NT-3-SCs) and TrkC (NT-3 receptor) gene-modified neural stem cells (NSCs, TrkC-NSCs) in a gelatin sponge scaffold could construct a tissue...
Paper Details
Title
Transplantation of tissue engineering neural network and formation of neuronal relay into the transected rat spinal cord
Published Date
Aug 5, 2016
Volume
109
Pages
40 - 54
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