An HPLC method for levofloxacin determination and its application in biomedical analysis
Abstract
Levofloxacin is a bacteriostatic L-isomer of ofloxacin. This drug is a third generation fluoroquinolone. Its activity strongly depends on its concentration and the AUC/MIC ratio is the best indication of drug exposure. A simple, specific and fast HPLC method with fluorescence detection for assay of levofloxacin level in human plasma was developed. The separation was performed on a reversed phase column. The mobile phase contained 0.4% solution...
Paper Details
Title
An HPLC method for levofloxacin determination and its application in biomedical analysis
Published Date
Jul 20, 2016
Volume
71
Issue
8
Pages
840 - 843
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