Published on May 1, 2005
· DOI :10.1142/9789812701220_0019
Ling Qin58
Estimated H-index: 58
Ge Zhang38
Estimated H-index: 38
+ 2 AuthorsPingcheung Leung1
Estimated H-index: 1
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688 Am J Health-Syst Pharm—Vol 61 Apr 1, 2004 JENNIFER CHENG, PEGGY LEE, and JOYCELYN LI are pharmacy students, University of California San Francisco (UCSF). CATHI E. DENNEHY, PHARM.D., and CANDY TSOUROUNIS, PHARM.D., are Associate Clinical Professors, School of Pharmacy, UCSF. Address correspondence to Dr. Dennehy at the Department of Clinical Pharmacy, University of California San Francisco, 521 Parnassus Avenue, Suite C-152, Box 0622, San Francisco, CA 94143 ( The author...
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Complementary medicine: evidence base, competence to practice and regulation. This paper describes the current status and evidence base for acupuncture, homeopathy, herbal and manipulative medicine, as well as the regulatory framework within which these therapies are provided. It also explores the present role of the Royal College of Physicians' Subcommittee on Complementary and Alternative Medicine (CAM) in relation to these developments. A number of CAM professions have encouraged the Royal Co...
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Abstract Densitometrically, the skeleton is currently conceived as ‘a systemically regulated mass of mineralized material that is born, grows, reaches a more or less high peak, and then declines faster or slower as to develop a correspondingly high or low fracture risk’. Alternatively, from a biomechanical point of view, the skeleton can be conceived as ‘a biomechanically-regulated structure that can be systemically disturbed (in the cybernetic sense), the strength of which depends on the intrin...
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For many decades, the Chinese have been using herbal medications to treat bone diseases. To examine effects of an extract of ten medicinal herbs on estrogen deficiency bone loss, ten-month-old female rats were randomly divided into three groups: ovariectomized (OVX), OVX treated with herbs (OVX-M) 4 ml/day by gavage, and OVX treated with estrogen (OVX-E) 10 mg subcutaneously (s.c.) twice per week. The bone mineral density (BMD) of the left femur (fBMD), spine (sBMD) and global body (gBMD) were m...
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Osteoporosis is a bone disease characterized by reduced bone mass, which leads to increased risk of bone fractures, and poses a significant risk to public health, especially in the elderly population. The traditional Chinese medicinal herb Epimedii has been utilized for centuries to treat bone fracture and bone loss. Icariin is a prenylated flavonol glycoside isolated from Epimedium herb, and has been shown to be the main bioactive component. This review provides a comprehensive survey of previo...
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Abstract Ethnopharmacological relevance Epimedium is a popular traditional herbal medicine worldwide that has long been used to relieve osteoporosis. The estrogenic properties of the herb are conferred by several phytoestrogens, such as flavonoids, lignans, and steroids. However, the poor understanding on the estrogen-like mechanism of Epimedium at the molecular and system levels limits the applications of this herb in osteoporosis treatment. Materials and methods In this study, systems pharmaco...
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Objectives Mast cells are believed to contribute to the pathogenesis of osteoporosis as their number is increased in osteoporotic bones. Herba Epimedii, Fructus Ligustri Lucidi and Fructus Psoraleae are three Chinese herbs traditionally for tonifying the ‘kidney system’ and a herbal formula (ELP) containing the respective herbs at the weight ratio of 5 : 4 : 1 was shown to prevent osteoporosis. This study evaluated if suppression of mast cell accumulation and activity contribute to the anti-oste...
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Abstract Background Epimedium -derived flavonoids (EFs) have a potential to treat established osteoporosis in postmenopausal women. However, one of the main disadvantages of the compound is the high volume and dosage during long-term administration period. Meanwhile, the beneficial effect of EFs on osteoporotic bone depends greatly on the intervention timing. Whether Icaritin (ICT), an active molecular compound from EFs, can exert beneficial effect on osteoporotic bone and whether the beneficial...
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Background Osteoporosis is a growing worldwide problem, with the greatest burden resulting from fractures. Nevertheless, the majority of fractures in adults occur in those with "osteopenia" (bone mineral density (BMD) only moderately lower than young normal individuals). Since long-term drug therapy is an expensive option with uncertain consequences and side effects, natural herbal therapy offers an attractive alternative. The purpose of this study is to evaluate the effect on BMD and safety of ...
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