Signaling from FGF Receptors in Development and Disease

Pages: 861 - 865
Published: Jan 1, 2003
Abstract
Fibroblast growth factor receptors (FGFRs) are members of the receptor tyrosine kinase family which consists of four structurally related members: FGFR 1, 2, 3, 4, and their alternatively spliced variants. Each receptor contains two to three immunoglobulin (Ig)-like domains in the extracellular region, an acidic box between Ig-1 and Ig-2, a transmembrane domain, and a split intracellular tyrosine kinase domain. Normal activation of FGFRs relies...
Paper Details
Title
Signaling from FGF Receptors in Development and Disease
Published Date
Jan 1, 2003
Pages
861 - 865
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