Tumor-related leukocytosis is associated with poor radiation response and clinical outcome in uterine cervical cancer patients

BackgroundTo evaluate response to radiation and clinical outcome of uterine cervical cancer patients with tumor-related leukocytosis (TRL) at initial diagnosis and during definitive radiotherapy.Patients and methodsWe retrospectively analyzed 2456 patients with stage IA–IVA uterine cervical cancer who received definitive radiotherapy with (37.4%) or without (62.6%) platinum-based chemotherapy between 1986 and 2012. TRL was defined as two or more...