Study of potential utility of new radiopharmaceuticals based on technetium-99m labeled derivative of glucose

R. Zeltchan; A. A. Medvedeva; I. G. Sinilkin; V. I. Chernov; E. S. Stasyuk; A. S. Rogov; E. A. Ilina; L. A. Larionova; V. S. Skuridin

doi:https://doi.org/10.1063/1.4960291

doi.org/10.1063/1.4960291

Study of potential utility of new radiopharmaceuticals based on technetium-99m labeled derivative of glucose

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..., V. S. Skuridin

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Published: Jan 1, 2016

Abstract

Purpose: to study the potential utility of 1-thio-D-glucose labeled with 99mTc for cancer imaging in laboratory animals. Materials and method: the study was carried out in cell cultures of normal CHO (Chinese hamster ovary cells CHO) and malignant tissues MCF-7 (human breast adenocarcinoma MCF-7). To evaluate the uptake of 99mTc-1-thio-D-glucose in normal and tumor tissue cells, 25 MBq of 1-thio-D-glucose labeled with 99mTc was added to the...

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Title

Study of potential utility of new radiopharmaceuticals based on technetium-99m labeled derivative of glucose

DOI

doi.org/10.1063/1.4960291

Published Date

Jan 1, 2016

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