Ivacaftor and symptoms of extra-oesophageal reflux in patients with cystic fibrosis and G551D mutation
Abstract
Extra-oesophageal reflux (EOR) may lead to microaspiration in patients with cystic fibrosis (CF), a probable cause of deteriorating lung function. Successful clinical trials of ivacaftor highlight opportunities to understand EOR in a real world study.Data from 12 patients with CF and the G551D mutation prescribed ivacaftor (150mg bd) was collected at baseline, 6, 26 and 52weeks. The changes in symptoms of EOR were assessed by questionnaire...
Paper Details
Title
Ivacaftor and symptoms of extra-oesophageal reflux in patients with cystic fibrosis and G551D mutation
Published Date
Jan 1, 2017
Journal
Volume
16
Issue
1
Pages
124 - 131
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Notes
History