Development and validation of chemoradio-prediction model using reverse-phase protein arrays in locally advanced cervical cancer

Objectives: The efficacy of radiation largely depends on the radiosensitivity of the tumor. In recent years, we have learned a great deal about the effects of apoptosis, cyclo-oxygenases, angiogenesis, hypoxia, and temperature on radiation, making it possible to manipulate the radiation response of cervical cancer to achieve a better treatment outcome. However, a multipanel prediction model has not been developed yet. Methods: To develop a...