Non-coplanar trajectories to improve organ at risk sparing in volumetric modulated arc therapy for primary brain tumors

Background and purposeTo evaluate non-coplanar volumetric modulated arc radiotherapy (VMAT) trajectories for organ at risk (OAR) sparing in primary brain tumor radiotherapy.Materials and methodsFifteen patients were planned using coplanar VMAT and compared against non-coplanar VMAT plans for three trajectory optimization techniques. A geometric heuristic technique (GH) combined beam scoring and Dijkstra’s algorithm to minimize the...