Cytotoxic effects of zearalenone and its metabolites and antioxidant cell defense in CHO-K1 cells
Abstract
Zearalenone (ZEA) and its metabolites (α-zearalenol; α-ZOL, β-zearalenol; β-ZOL) are secondary metabolites of Fusarium fungi that produce cell injury. The present study explores mycotoxin-induced cell damage and cellular protection mechanisms in CHO-K1 cells. Cytotoxicity has been determined by reactive oxygen species (ROS) production and DNA damage. ROS production was determined using the fluorescein assay and DNA strand breakage by comet...
Paper Details
Title
Cytotoxic effects of zearalenone and its metabolites and antioxidant cell defense in CHO-K1 cells
Published Date
Oct 1, 2016
Journal
Volume
96
Pages
43 - 49
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Notes
History