Isolated limb infusion chemotherapy with or without hemofiltration for recurrent limb melanoma

Aim: To better define the efficacy and the safety of intra-arterial infusion performed with or without hemofiltration for recurrent limb melanoma. Methods: Patients with the following characteristics were included in the study: recurrent limb melanoma not indicated for surgical resection, measurable disease in the extremity, >18 years, performances status (ECOG) was 0-1 and life expectancy of at least 6 months. Twenty nine consecutive patients...