Chronic Diffuse Lung Diseases

Published on Jan 1, 2018
· DOI :10.1016/B978-0-323-44284-8.00008-9
Mikiko Hashisako8
Estimated H-index: 8
,
Junya Fukuoka37
Estimated H-index: 37
+ 0 AuthorsMaxwell L. Smith1
Estimated H-index: 1
Sources
Abstract
Abstract Chronic diffuse lung diseases involve a spectrum of nonneoplastic inflammatory conditions that affect the lung parenchyma. This chapter reviews the spectrum of disease including idiopathic interstitial pneumonias, pulmonary manifestations of systemic collagen vascular disease, diffuse eosinophilc lung disease, drug-associated lung disease, diffuse granulomatous lung disease, and a variety of miscellaneous diseases that defy classification. Individual entities are reviewed, followed by a section highlighting a practical approach to the four most common patterns of injury encountered in practice.
References499
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We describe 6 patients with chronic interstitial lung disease in whom open lung biopsies showed respiratory bronchiolitis. The patients ranged from 28 to 46 yr of age (mean, 36 yr) and included 5 men and 1 woman. All were heavy cigarette smokers. Five had respiratory symptoms, most commonly cough and dyspnea. Diffuse interstitial infiltrates were seen on chest radiographs in 5 and bibasilar atelectasis in 1. Pulmonary function tests showed mild to moderate restriction in 4 and decreased diffusin...
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