Cardiovascular safety of dipeptidyl peptidase-4 inhibitors: recent evidence on heart failure.
Abstract
The cardiovascular safety of DPP4 inhibitors as a class, especially in regards to heart failure, has been questioned after the publication of first trials (SAVOR-TIMI 53 and EXAMINE) assessing the cardiovascular risks of DPP4 inhibitors alogliptin and sitagliptin in 2013. Although there were no increased risks in composite cardiovascular outcomes, the SAVOR-TIMI 53 trial reported a 27% increase in hospitalization for heart failure in diabetic...
Paper Details
Title
Cardiovascular safety of dipeptidyl peptidase-4 inhibitors: recent evidence on heart failure.
Published Date
Jan 1, 2016
Journal
Volume
8
Issue
5
Pages
2450 - 8
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