Contribution of collagen adhesion receptors to tissue fibrosis
Abstract
Fibrosis is the result of a wound-healing response that fails to restore normal tissue structure function. One of the critical hallmarks of fibrosis is disrupted collagen remodeling. In tissue homeostasis, the production, deposition and organization of collagen is balanced by the degradation and remodeling of collagen within the existing matrix. After injury or chronic infection, tissues initiate a wound-healing response that is intended to...
Paper Details
Title
Contribution of collagen adhesion receptors to tissue fibrosis
Published Date
Jun 28, 2016
Journal
Volume
365
Issue
3
Pages
521 - 538
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