Testing for Anti-PBP Antibody Is Not Useful in Diagnosing Autoimmune Pancreatitis

OBJECTIVES: Autoimmune pancreatitis (AIP) is a rare form of chronic pancreatitis, clinically mimicking pancreatic cancer. In 2009, a serological diagnostic test detecting antibodies against plasminogen-binding protein (PBP) ofHelicobacter pyloriwas reported with outstanding test performances (NEJM 361:135). We aimed to validate these findings. METHODS: Between March 2007 and May 2011, sera were collected from consecutive patients presenting with...