Review paper

The role of phenotypic plasticity in the escape of cancer cells from targeted therapy

Volume: 122, Pages: 1 - 9
Published: Dec 1, 2016
Abstract
Targeted therapy has proven to be beneficial at producing significant responses in patients with a wide variety of cancers. Despite initially impressive responses, most individuals ultimately fail these therapies and show signs of drug resistance. Very few patients are ever cured. Emerging evidence suggests that treatment of cancer cells with kinase inhibitors leads a minor population of cells to undergo a phenotypic switch to a more...
Paper Details
Title
The role of phenotypic plasticity in the escape of cancer cells from targeted therapy
Published Date
Dec 1, 2016
Volume
122
Pages
1 - 9
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