Interaction of calcitonin gene related peptide (CGRP) and substance P (SP) in human skin
Abstract
Calcitonin gene related peptide (CGRP) and substance P (SP) are neuropeptides that are simultaneously released from nociceptive C-fibers. CGRP is a potent vasodilator, inducing a long-lasting increase in superficial skin blood flow, whereas SP induces only a brief vasodilation but a significant plasma extravasation. CGRP and SP may play important roles in the pathophysiology of various pain states but little is known about their interaction....
Paper Details
Title
Interaction of calcitonin gene related peptide (CGRP) and substance P (SP) in human skin
Published Date
Oct 1, 2016
Journal
Volume
59
Pages
57 - 62
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Notes
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