Toxic epidermal necrolysis
Abstract
Toxic epidermal necrolysis is the prototype of a proapoptotic disease characterized by system CD95 dysrregulation. Drugs constitute the main antigenic triggers. Hystopatologically it is characterized by epidermis detachment and necrosis with apoptotic keratinocytes. Clinical presentation includes erithematous-ampullous lesions in the skin and mucous membranes. It is associated with serious complications such as severe sepsis and septic shock....
Paper Details
Title
Toxic epidermal necrolysis
Published Date
Jul 1, 2006
Journal
Volume
142
Issue
4
Pages
337 - 340
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