Altered proliferation and networks in neural cells derived from idiopathic autistic individuals
Abstract
Autism spectrum disorders (ASD) are common, complex and heterogeneous neurodevelopmental disorders. Cellular and molecular mechanisms responsible for ASD pathogenesis have been proposed based on genetic studies, brain pathology and imaging, but a major impediment to testing ASD hypotheses is the lack of human cell models. Here, we reprogrammed fibroblasts to generate induced pluripotent stem cells, neural progenitor cells (NPCs) and neurons from...
Paper Details
Title
Altered proliferation and networks in neural cells derived from idiopathic autistic individuals
Published Date
Jul 5, 2016
Journal
Volume
22
Issue
6
Pages
820 - 835
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