Interleukin-29 Enhances Synovial Inflammation and Cartilage Degradation in Osteoarthritis
Abstract
We have recently shown that IL-29 was an important proinflammatory cytokine in pathogenesis of rheumatoid arthritis (RA). Inflammation also contributes to the pathogenesis of osteoarthritis (OA). The aim of this study was to investigate the effect and mechanism of IL-29 on cytokine production and cartilage degradation in OA. The mRNA levels of IL-29 and its specific receptor IL-28Ra in peripheral blood mononuclear cells (PBMCs) were...
Paper Details
Title
Interleukin-29 Enhances Synovial Inflammation and Cartilage Degradation in Osteoarthritis
Published Date
Jan 1, 2016
Journal
Volume
2016
Pages
1 - 13
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