Comparison of dose-response curves for chromosomal aberrations established by chromosome painting and conventional analysis

Purpose: To establish 60Co gamma -ray dose-response curves for dicentrics and translocations visualized by chromosome painting and for dicentrics analysed after conventional solid staining. Materials and methods : Analysis of chromosomal aberrations was performed on peripheral blood lymphocytes obtained from 48 h old cultures of irradiated whole blood. Dicentrics were scored from Giemsa-stained preparations, and bi-coloured dicentrics and...