Role of heme in bromine‐induced lung injury

Bromine (Br 2 ) gas inhalation poses an environmental and occupational hazard resulting in high morbidity and mortality. In this review, we underline the acute lung pathology (within 24 h of exposure) and potential therapeutic interventions that may be utilized to mitigate Br 2 ‐induced human toxicity. We discuss our latest published data, which suggest that an increase in heme‐dependent tissue injury underlies the pathogenesis of Br 2 toxicity....