Evidence for participation of neutrophil gelatinase-associated lipocalin/matrix metalloproteinase-9 (NGAL•MMP-9) complex in the inflammatory response to infection in pregnancies complicated by preterm birth

Volume: 76, Issue: 2, Pages: 108 - 117
Published: Jun 1, 2016
Abstract
Neutrophil gelatinase-associated lipocalin (NGAL) is expressed in neutrophils and involved in innate immunity by sequestering iron. NGAL's ability to complex with matrix metalloproteinase-9 (MMP-9) and extend its gelatinolytic activity led us to investigate its role in pregnancies complicated by preterm birth (PTB) and intra-amniotic infection/inflammation (IAI).We assayed the amniotic fluid (AF) levels of NGAL and MMP-9 in 308 women that had a...
Paper Details
Title
Evidence for participation of neutrophil gelatinase-associated lipocalin/matrix metalloproteinase-9 (NGAL•MMP-9) complex in the inflammatory response to infection in pregnancies complicated by preterm birth
Published Date
Jun 1, 2016
Volume
76
Issue
2
Pages
108 - 117
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