Gene rearrangement in B- and T-lymphoproliferative disease detected by the polymerase chain reaction [see comments]
Abstract
Gene rearrangement and monoclonality have been detected in normal cells and in lymphoproliferative disease by using the polymerase chain reaction and primers for the V and J regions of the Ig heavy chain gene or T-cell receptor gamma-chain gene. Using the Ig primers monoclonality was detected in 20 of 20 normal B-lymphocyte clones and in 39 of 52 cases of various types of B-lymphoproliferative disease, but not in 11 cases of...
Paper Details
Title
Gene rearrangement in B- and T-lymphoproliferative disease detected by the polymerase chain reaction [see comments]
Published Date
Jul 1, 1991
Journal
Volume
78
Issue
1
Pages
192 - 196
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Notes
History