A case of autoimmune hepatitis accompanied by systemic lupus erythematosus

Published on Jan 1, 2007in The Korean Journal of Internal Medicine
Kee Tae Park4
Estimated H-index: 4
,
Kyung Yup Kim3
Estimated H-index: 3
+ 3 AuthorsHo Dong Kim5
Estimated H-index: 5
Sources
Abstract
Autoimmune hepatitis accompanied by systemic erythematosus lupus is rare. Usually, lupus-related advanced liver involvement is indistinguishable from autoimmune hepatitis accompanied by lupus, as they share common clinical, biochemical, serological, and histological manifestations. However, each disease has its own diagnostic criteria, and they have been defined as two different categories. Therefore, distinguishing between the two diseases is important to determine the correct diagnosis and treatment. A 41-year-old woman was hospitalized with jaundice and a malar rash. The patient met the diagnostic criteria of both systemic erythematosus lupus and autoimmune hepatitis. After corticosteroid treatment, the patient's condition improved. Therefore, we report our experience of a rare case of autoimmune hepatitis accompanied by systemic erythematosus lupus with a review of the literature.
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전신성 홍반성 루푸스 자체에 의한 간염은 드물게 발생하며, 자가면역성 간염과 감별을 요한다. 저자들은 자가면역성 간염과 유사하게 표현된 루푸스 간염에서 간 조직검사의 중요성을 경험하였기에 문헌고찰과 함께 보고하는 바이다.
Autoimmune hepatitis (AIH), primary sclerosing cholangitis (PSC), and primary biliary cirrhosis (PBC) are the major immune-mediated chronic liver diseases. They are characterized by circulating autoantibodies, hypergammaglobulinemia, unique clinical features, and associations with other autoimmune diseases, such as inflammatory bowel disease and autoimmune thyroiditis. Primary biliary cirrhosis is known to be associated with inflammatory bowel disease, such as ulcerative colitis. On the other ha...