Tetherin/BST-2 promotes dendritic cell activation and function during acute retrovirus infection
Abstract
Tetherin/BST-2 is a host restriction factor that inhibits retrovirus release from infected cells in vitro by tethering nascent virions to the plasma membrane. However, contradictory data exists on whether Tetherin inhibits acute retrovirus infection in vivo . Previously, we reported that Tetherin-mediated inhibition of Friend retrovirus (FV) replication at 2 weeks post-infection correlated with stronger natural killer, CD4+ T and CD8+ T cell...
Paper Details
Title
Tetherin/BST-2 promotes dendritic cell activation and function during acute retrovirus infection
Published Date
Feb 5, 2016
Journal
Volume
6
Issue
1
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