Primary-cilium-dependent autophagy controls epithelial cell volume in response to fluid flow

Volume: 18, Issue: 6, Pages: 657 - 667
Published: Jun 1, 2016
Abstract
Autophagy is an adaptation mechanism that is vital for cellular homeostasis in response to various stress conditions. Previous reports indicate that there is a functional interaction between the primary cilium (PC) and autophagy. The PC, a microtubule-based structure present at the surface of numerous cell types, is a mechanical sensor. Here we show that autophagy induced by fluid flow regulates kidney epithelial cell volume in vitro and in...
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Paper Details
Title
Primary-cilium-dependent autophagy controls epithelial cell volume in response to fluid flow
Published Date
Jun 1, 2016
Volume
18
Issue
6
Pages
657 - 667
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