Leptin promotes proliferation and metastasis of human gallbladder cancer through OB-Rb leptin receptor

Volume: 49, Issue: 1, Pages: 197 - 206
Published: May 18, 2016
Abstract
Emerging evidence has shown that leptin, an adipocyte-derived cytokine that is closely associated with obesity, play a significant role in carcinogenesis and tumorigenesis. However, its impact on gallbladder cancer (GBC) remains unclear. In this study, we firstly found that leptin and its functional receptor OB-Rb were significantly co-expressed in human GBC tissues and cell lines, the content of which were higher than those in normal human...
Paper Details
Title
Leptin promotes proliferation and metastasis of human gallbladder cancer through OB-Rb leptin receptor
Published Date
May 18, 2016
Volume
49
Issue
1
Pages
197 - 206
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