Higher‐order oligomerization promotes localization of SPOP to liquid nuclear speckles

Volume: 35, Issue: 12, Pages: 1254 - 1275
Published: Jun 15, 2016
Abstract
null Membrane‐less organelles in cells are large, dynamic protein/protein or protein/RNA assemblies that have been reported in some cases to have liquid droplet properties. However, the molecular interactions underlying the recruitment of components are not well understood. Herein, we study how the ability to form higher‐order assemblies influences the recruitment of the speckle‐type POZ protein (SPOP) to nuclear speckles. SPOP, a cullin‐3‐RING...
Paper Details
Title
Higher‐order oligomerization promotes localization of SPOP to liquid nuclear speckles
Published Date
Jun 15, 2016
Volume
35
Issue
12
Pages
1254 - 1275
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