Development of an ANN optimized mucoadhesive buccal tablet containing flurbiprofen and lidocaine for dental pain
Abstract
A novel mucoadhesive buccal tablet containing flurbiprofen (FLB) and lidocaine HCl (LID) was prepared to relieve dental pain. Tablet formulations (F1-F9) were prepared using variable quantities of mucoadhesive agents, hydroxypropyl methyl cellulose (HPMC) and sodium alginate (SA). The formulations were evaluated for their physicochemical properties, mucoadhesive strength and mucoadhesion time, swellability index and in vitro release of active...
Paper Details
Title
Development of an ANN optimized mucoadhesive buccal tablet containing flurbiprofen and lidocaine for dental pain
Published Date
May 28, 2016
Journal
Volume
66
Issue
2
Pages
245 - 256
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