MicroRNA‐590‐5p Stabilizes Runx2 by Targeting Smad7 During Osteoblast Differentiation

Volume: 232, Issue: 2, Pages: 371 - 380
Published: Jun 15, 2016
Abstract
Mesenchymal stem cells (MSCs) are multipotent cells and their differentiation into the osteoblastic lineage is strictly controlled by several regulators, including microRNAs (miRNAs). Runx2 is a bone transcription factor required for osteoblast differentiation. Here, we used in silico analysis to identify a number of miRNAs that putatively target Runx2 and its co‐factors to mediate both positive and negative regulation of osteoblast...
Paper Details
Title
MicroRNA‐590‐5p Stabilizes Runx2 by Targeting Smad7 During Osteoblast Differentiation
Published Date
Jun 15, 2016
Volume
232
Issue
2
Pages
371 - 380
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