[The distribution and clinical significance of IgG subclasses of anti-glomerular basement membrane antibodies].

It was reported that major subclasses of anti-glomerular basement membrane (GBM) antibody were IgG1 and IgG4. The IgG1 subclass was mainly found in male patients and IgG4 subclass in female patients with anti-GBM disease. This study investigates the distribution of anti-GBM IgG subclasses and their association with clinical characteristics.Sera from 50 patients diagnosed as anti-GBM disease during 1991-2003 were collected. The anti-GBM...