[The role of iron and hepcidin in hepatic fibrosis].
Abstract
Liver iron overload can be found in a number of different chronic liver diseases. Iron is proposed to play a role in promoting hepatic fibrosis by various mechanisms, including iron-catalyzed production of free radical and lipid peroxidation, alteration of essential biomolecules, triggering cell apoptosis and necrosis, and activation and transformation of the hepatic stellate cell into a myofibroblastic cell. Recent evidences demonstrate that...
Paper Details
Title
[The role of iron and hepcidin in hepatic fibrosis].
Published Date
Jun 1, 2010
Journal
Volume
41
Issue
3
Pages
183 - 8
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